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Selectively Decreased Expression of Peroxiredoxins Induced by Silica in Pulmonary Epithelial Cells
Hye Lim Lee, Young Sun Kim, Joo Hun Park, Wou Young Chung, Kyu Sung Lee, Yoon Jung Oh, Seung Soo Sheen, Kwang Joo Park, Sung Chul Hwang
Korean J Intern Med. 2009;24(3):220-226. Published online August 26, 2009
Background/AimsPeroxiredoxin (Prx) belongs to a ubiquitous family of antioxidant enzymes that regulates many cellular processes through intracellular oxidative signal transduction pathways. Silica-induced lung damage involves reactive oxygen species (ROS) that trigger subseque..
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Successful Treatment of Small-Cell Lung Cancer With Irinotecan in a Hemodialysis Patient With End-Stage Renal Disease
Dong Min Kim, Hyun Lee Kim, Choon Hae Chung, Chi Young Park
Korean J Intern Med. 2009;24(1):73-75. Published online March 6, 2009
The prognosis of patients with end-stage renal disease has improved with advances in hemodialysis techniques. However, many patients who undergo hemodialysis suffer from various types of cancer. Limited data is available to guide clinical management of these patients who may have impaired renal f..
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EGFR and KRAS Mutations in Patients With Adenocarcinoma of the Lung
Tae Won Jang, Chul Ho Oak, Hee Kyung Chang, Soon Jung Suo, Mann Hong Jung
Korean J Intern Med. 2009;24(1):48-54. Published online March 6, 2009
Background/AimsMutations of the epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene (KRAS) are important in the pathogenesis of lung cancer, and recent reports have revealed racial and geographical differences in mutation expression.
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Docetaxel Monotherapy as Second-Line Treatment for Pretreated Advanced Non-Small Cell Lung Cancer Patients
Yoon Ho Ko, Myung Ah Lee, Yeong Seon Hong, Kyung Shik Lee, Hyun Jin Park, Ie Ryung Yoo, Yeon Sil Kim, Young Kyoon Kim, Keon Hyun Jo, Young Pil Wang, Kyo Young Lee, Jin Hyoung Kang
Korean J Intern Med. 2007;22(3):178-185. Published online September 30, 2007
BackgroundSecond-line chemotherapy offers advanced non-small cell lung cancer (NSCLC) patients a small, but significant increase in survival. Docetaxel is usually administered as a 3-week schedule, yet there is significant toxicity with this therapy. Therefore, a weekly schedu..
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Pancreatitis from Metastatic Small Cell Lung Cancer: Successful Treatment with Endoscopic Intrapancreatic Stenting
Jong-Shin Woo, Kwang Ro Joo, Yong Sik Woo, Jae Young Jang, Young Woon Chang, Joung Il Lee, Rin Chang
Korean J Intern Med. 2006;21(4):256-261. Published online December 31, 2006
Lung cancer metastases can occur in almost any organ. However, metastasis of small cell lung cancer to the pancreas is rare. Moreover, not all cases present with clinically diagnosed pancreatitis. We recently treated a patient with small cell lung carcinoma that invaded the pancreatic duct causin..
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Photodynamic Therapy in Early Lung Cancer: A Report of Two Cases
Tae Won Jang, Hee Kyoo Kim, Chul Ho Oak, Mann Hong Jung
Korean J Intern Med. 2006;21(3):178-182. Published online September 30, 2006
Photodynamic therapy (PDT) that is based on the science of photochemistry has been recognized as a lung sparing local therapeutic modality that can achieve remarkable responses. It is an alternative treatment for early stage lung cancer patients who have poor lung function or multiple sites of ca..
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Pancreatic Metastasis and Obstructive Jaundice in Small Cell Lung Carcinoma
In Beom Jeong, Sun Moon Kim, Tae Hee Lee, Euyi Hyeog Im, Kyu Chan Huh, Young Woo Kang, Young Woo Choi
Korean J Intern Med. 2006;21(2):132-135. Published online June 30, 2006
Primary lung cancer frequently metastasizes to distant organs. The pancreas is a relatively infrequent site of metastasis. Furthermore, obstructive jaundice resulting from pancreatic metastasis is extremely rare. This paper examines the case of a 65-year-old woman with small cell lung cancer init..
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ThE Role of Endoscopic Surgery for Completely Obstructive Endobronchial Benign Tumor
Jae-Chol Choi, Chang Min Yu, Yon Ju Ryu, Kyeongman Jeon, Kyoung A Choi, O Jung Kwon, Hojoong Kim
Korean J Intern Med. 2006;21(1):15-19. Published online March 30, 2006
BackgroundThe improving techniques of therapeutic bronchoscopy have been replacing conventional surgery for resecting endobronchial benign tumor. However, there could be some limitation for performing bronchoscopic intervention for the patients with complete bronchial obstruct..
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Non-small Cell Lung Cancer Initially Presenting with Intracardiac Metastasis
Jung Han Kim, Joo Young Jung, Young Iee Park, Sang Ik Hwang, Chull Sung Jung, Sang Hak Lee, Chong Woo Yoo
Korean J Intern Med. 2005;20(1):86-89. Published online March 31, 2005
Intracardiac metastasis as the initial presentation of malignant neoplasm is very rare. We report here on a 64-year-old man with non-small cell lung cancer (NSCLC) initially presenting with intracardiac metastasis which was identified with 18-F fluorodeoxyglucose positron emission tomography (FDG..
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